How bacteria rewire the host
Which contacts between bacterial and human proteins make infection possible? We map host–pathogen protein interactions, relate network organisation to bacterial fitness, and study the complexes that bacteria use to enter, survive and proliferate inside host cells. Our work on imperfect structural mimicry examines how bacterial proteins resemble host interfaces while retaining features that could help distinguish microbial targets from human ones.
Our approach
Host–pathogen interactomics · Network analysis · Infection phenotypes
